De novo regeneration of Scrophularia yoshimurae YAMAZAKI (Scrophulariaceae) and quantitative analysis of harpagoside, an iridoid glucoside, formed in aerial and underground parts of in vitro propagated and wild plants by HPLC

CMUR > College of Pharmacy > Graduate Institute of Chinese Pharmaceutical Science > Journal articles > Item 310903500/30716

Please use this identifier to cite or link to this item: http://ir.cmu.edu.tw/ir/handle/310903500/30716

Title:	De novo regeneration of Scrophularia yoshimurae YAMAZAKI (Scrophulariaceae) and quantitative analysis of harpagoside, an iridoid glucoside, formed in aerial and underground parts of in vitro propagated and wild plants by HPLC
Authors:	Sagare, AP;Kuo, CL;Chueh, FS;Tsay, HS
Contributors:	藥學院中藥所;Taiwan Agr Res Inst, Dept Agron, Taichung 41301, Taiwan;Jen Te Hsiang, Tainan, Taiwan;China Med Coll, Inst Chinese Pharmaceut Sci, Taichung 40421, Taiwan
Date:	2001
Issue Date:	2010-09-24 15:00:31 (UTC+8)
Publisher:	PHARMACEUTICAL SOC JAPAN
Abstract:	To evaluate the clinical value of whole body positron emission tomography (PET) with 18F-fluoro-2-deoxyglucose (FDG) in recurrent cervical cancer, the records of 20 patients who underwent FDG-PET scans were reviewed to detect local recurrence, pelvic/para-aortic lymph node metastases and distal metastases. The final diagnosis was based on operative, histopathological findings or clinical follow-up for longer than one year. FDG-PET accurately detected 18 patients with recurrent diseases (12 patients with local recurrences, 16 patients with pelvic lymph node metastases, 14 patients with para-aortic lymph node metastases and 4 patients with distal metastases Of other sites). However, 2 patients with local recurrences had false-negative FDG-PET results as well as I patient without local recurrence and I patient without pelvic lymph node metastases who had false-positive FDG-PET results. The overall sensitivity and specificity of FDG-PET for patients were 90% and 100%, for local recurrence were 86% and 92%, for pelvic lymph node metastases were 100% and 94%, for para-aortic lymph node metastases were 100% and 100% and for distal metastases were 100% and 100%, respectively. In conclusion, whole body FDG-PET is a useful diagnostic tool in the evaluation of recurrent cervical cancer. It appears to be promising for detecting recurrent cervical cancer, lymph node metastases and distal metastases.
Relation:	BIOLOGICAL & PHARMACEUTICAL BULLETIN 24(11):1311-1315
Appears in Collections:	[Graduate Institute of Chinese Pharmaceutical Science] Journal articles

Files in This Item:

There are no files associated with this item.

Loading...