DAT polymorphism and diverse clinical manifestations in methamphetamine abusers

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Title:	DAT polymorphism and diverse clinical manifestations in methamphetamine abusers
Authors:	Liu, HC;Lin, SK;Liu, SK;Chen, SL;Hu, CJ;Chang, JG;Leu, SJ
Contributors:	附設醫院醫研部;Taipei Med Univ, Grad Inst Cell & Mol Biol, Dept Psychiat, Taipei, Taiwan;Taipei City Psychiat Ctr, Dept Addict Sci, Taipei, Taiwan;Taipei City Psychiat Ctr, Mol Psychiat Lab, Taipei, Taiwan;En Chu Kong Hosp, Dept Psychiat, Taipei, Taiwan;Taipei Municipal Jen Ai Hosp, Dept Neurol, Taipei, Taiwan;Taipei Municipal Jen Ai Hosp, Mol Med Lab, Taipei, Taiwan;China Med Coll Hosp, Div Mol Med, Dept Med Res, Taichung, Taiwan
Date:	2004
Issue Date:	2010-09-24 15:00:20 (UTC+8)
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Abstract:	A high performance liquid chromatographic method was developed for simultaneous determination of 5 whitening ingredients: magnesium ascorbyl phosphate, ascorbyl glucoside, kojic acid, arbutin and hydroquinone decomposed from arbutin in cosmetics. Samples were extracted with 0.05 M KH2PO4 buffer solution (pH 2.5) and analyzed using a Cosmosil 5 C18-AR-II column. A mixture of 0.05 M KH2PO4 buffer solution (pH 2.5) and methanol (99: 1, v/v) was used as mobile phase. The UV detector was set at 280 nm. Pyridoxine was used as an internal standard. The related coefficients, R-2, of regression equations of the 5 standard curves were 0.9998-1.0000. The relative standard deviations of the 5 ingredients for intraday and interday analysis were less than 2.4%. The average recoveries of these 5 ingredients spiked in sample ranged from 93.5% to 103.3%. The relative standard deviations of average recoveries were less than 1.3%. The limits of quantitation in cosmetics were 80.0, 20.0, 3.0, 15.0 and 10.0 mug/mL for magnesium ascorbyl phosphate, ascorbyl glucoside, kojic acid, arbutin and hydroquinone, respectively.
Relation:	PSYCHIATRIC GENETICS 14(1):33-37
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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