Vascular endothelial growth factor-C expression and invasive phenotype in ovarian carcinomas

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Title:	Vascular endothelial growth factor-C expression and invasive phenotype in ovarian carcinomas
Authors:	Ueda, M;Hung, YC;Terai, Y;Kanda, K;Kanemura, M;Futakuchi, H;Yamaguchi, H;Akise, D;Yasuda, M;Ueki, M
Contributors:	醫學院醫學系婦產學科;Osaka Med Coll, Dept Obstet & Gynecol, Takatsuki, Osaka 5698686, Japan;China Med Coll, Dept Obstet & Gynecol, Taichung, Taiwan
Date:	2005
Issue Date:	2010-09-24 14:58:54 (UTC+8)
Publisher:	AMER ASSOC CANCER RESEARCH
Abstract:	Leukocyte count, neutrophil percentage, and C-reactive protein (CRP) have been shown to give valuable information in the diagnosis of acute appendicitis. However, whether these laboratory tests have the same clinical applicability in the elderly as in young patients remains unclear. This retrospective study aimed to clarify the role of these tests in the diagnosis of acute appendicitis in patients aged 60 years or over. Eighty-five consecutive elderly patients underwent appendectomy for suspected acute appendicitis during a 30-month period. Histologically verified appendicitis was found in 77 of the 85 patients (90.6%). There was no significant difference in leukocyte counts or CRP values between patients with acute appendicitis and those with a normal appendix. The sensitivities of leukocyte count, neutrophil percentage, and CRP in the diagnosis of acute appendicitis were 71.4 per cent, 88.3 per cent, and 90 per cent, respectively, while the specificities were 37.5 per cent, 25 per cent, and 37.5 per cent, respectively. Of 77 patients with acute appendicitis, only two had all three tests simultaneously normal. In conclusion, patients with normal results in all three tests are highly unlikely to have acute appendicitis and should be evaluated with extra caution before surgery.
Relation:	CLINICAL CANCER RESEARCH 11(9):3225-3232
Appears in Collections:	[School of Medicine] Journal articles

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