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    CMUR > College of Medicine > School of Medicine > Journal articles >  Item 310903500/30616
    Please use this identifier to cite or link to this item: http://ir.cmu.edu.tw/ir/handle/310903500/30616


    Title: Correlation between vascular endothelial growth factor-C expression and invasion phenotype in cervical carcinomas
    Authors: Ueda, M;Terai, Y;Yamashita, Y;Kumagai, K;Ueki, K;Yamaguchi, H;Akise, D;Hung, YC;Ueki, M
    Contributors: 醫學院醫學系婦產學科;Osaka Med Coll, Dept Obstet & Gynecol, Osaka 5698686, Japan;China Med Coll, Dept Obstet & Gynecol, Taichung, Taiwan
    Date: 2002
    Issue Date: 2010-09-24 14:58:44 (UTC+8)
    Publisher: WILEY-LISS
    Abstract: Purpose. To describe a patient with scleral dellen after pterygium excision with intraoperative mitomycin C. Methods. Case report and MEDLINE review of the medical literature on scleral dellen after bare sclera technique. Results. A 48-year-old man had a left nasal pterygium excised by the bare sclera technique with intraoperative mitomycin C. Eight days after surgery, the patient noticed a small black spot in the bare sclera area with mild irritation. Slit-lamp examination repealed a focal area of extreme thinning, centered on the nonepithelialized bare sclera. surrounded by edematous conjunctiva. The ciliary body was visible through the thin and dry scleral lesion. After topical lubricant therapy, the scleral lesion appeared normal thickness and white in color 3 days later. Therapy was continued until the sclera epithelialized. Conclusions. Scleral dellen is an early postoperative complication of bare sclera technique owing to delayed conjunctival wound closure. Hydration of the thinned sclera will rapidly thicken it. However, medical therapy should be continued until the surrounding conjunctiva has flattened and the sclera has epithelialized, Surgical wound closure is an alternative management and may be the way to prevent scleral dellen formation after bare sclera technique. All patients after bare sclera surgery should be followed up until the conjunctival wound has healed. If delayed healing is found, frequent artificial tears. patching, or surgical intervention is necessary.
    Relation: INTERNATIONAL JOURNAL OF CANCER 98(3):335-343
    Appears in Collections:[School of Medicine] Journal articles

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