Lumbar bone mineral density in prostate cancer patients with bone metastases

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Title:	Lumbar bone mineral density in prostate cancer patients with bone metastases
Authors:	Chang, CH;Tsai, CS;Jim, YF;Wu, HC;Lin, CC;Kao, A
Contributors:	附設醫院醫研部;China Med Coll Hosp, Dept Med Res, Taichung 404, Taiwan;China Med Coll Hosp, Dept Urol, Taichung 404, Taiwan;China Med Coll Hosp, Dept Radiol, Taichung 404, Taiwan;China Med Coll Hosp, Dept Family Med, Taichung 404, Taiwan;Tzu Chi Coll Technol, Hualien, Taiwan
Date:	2003
Issue Date:	2010-09-24 14:58:26 (UTC+8)
Publisher:	MARCEL DEKKER INC
Abstract:	BACKGROUND. It is known that 18-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) is effective in the early detection of residual/recurrent nasopharyngeal carcinomas (NPC). To compare FDG-PET with the conventional magnetic resonance imaging (MRI) for the detection of residual/recurrent NPC, the authors studied 67 follow-up cases of patients with NPC using both FDG-PET and MRI. METHODS. From February 1997 to February 2001, 67 NPC patients (14 women, 53 men; age range, 16-67 years; mean age, 46.6 +/- 12.5 years) were recruited. Both FDG-PET and MRI of the head and neck area for each patient were performed at least 4 months (duration range, 4-70 months; mean, 14 +/- 13.5 months) after radiotherapy or radiotherapy with concurrent chemotherapy. The final diagnosis was confirmed by biopsy or clinical follow-up for at least 6 months. RESULTS. The sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) of FDG-PET images were 100%, 93.4%, 95.5%, 87.5%, and 100%, respectively. In contrast, the sensitivity, specificity, accuracy, PPV, and NPV of the MRI scans were 61.9%, 43.5%, 49.3%, 33.3%, and 70.0%, respectively. CONCLUSIONS. The results of the current study suggest that FDG-PET is much more effective than MRI in detecting residual/recurrent NPC. (C) 2003 American Cancer Society.
Relation:	ENDOCRINE RESEARCH 29(2):177-182
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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