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    題名: Effective treatment for mixed urinary incontinence with a pubovaginal sling
    作者: Chou, ECL;Flisser, AJ;Panagopoulos, G;Blaivas, JG
    貢獻者: 醫學院醫學系泌尿學科;China Med Coll, Sch Med, Dept Urol, Taichung, Taiwan;China Med Coll Hosp, Dept Urol, Taichung, Taiwan;Cornell Univ, Joan & Sanford Weil Coll Med, Dept Clin Obstet & Gynecol, Ithaca, NY USA;Lenox Hill Hosp, Dept Res, New York, NY 10021 USA;Lenox Hill Hosp, Dept Urogynecol, New York, NY 10021 USA
    日期: 2003
    上傳時間: 2010-09-24 14:56:59 (UTC+8)
    出版者: LIPPINCOTT WILLIAMS & WILKINS
    摘要: The aim of this study was to investigate the association of tumor necrosis factor alpha (TNFalpha) gene promoter polymorphisms in Chinese patients with rheumatoid arthritis (RA) in central Taiwan. A total of 106 RA patients and 253 normal controls were studied. Polymerase chain reaction (PCR)-based restriction analysis was used to identify A/G polymorphism at position 308 in the promoter region of the TNFalpha, which is located at 6q21.3. For the genotype of TNFalpha-308 polymorphism, there was no statistically significant difference between RA patients and normal controls (Fisher's exact test, P=0.82). Additionally, no statistical association in the distribution of TNFalpha-308 polymorphism between rheumatoid factor (RF)-positive and -negative patients was noted. The lack of an association of TNFalpha-308 polymorphism with RA and RF in our study implies that TNFalpha-308 polymorphism cannot serve as a candidate gene marker for screening RA patients in Taiwan.
    關聯: JOURNAL OF UROLOGY 170(2):494-497
    顯示於類別:[醫學系] 期刊論文

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