The effect of acupuncture on cardiac muscle cells and blood pressure in spontaneous hypertensive rats.

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Title:	The effect of acupuncture on cardiac muscle cells and blood pressure in spontaneous hypertensive rats.
Authors:	吳宏乾(Hung-Chien Wu);林昭庚(教授，研，董事);(Chun-Hsieh Chu);張永賢(Yung-Hsien Chang);(Gung-Gwo Chang);謝慶良(Ching-Liang Hsieh);蔡欣潔(Angela Hsin -Chieh T);(Kwo-Chang Ueng);郭薇雯(Wei-Wen Kuo);(James A Lin);(Jer-Yuh Liu);(Chih-Yang Huagn)
Contributors:	中醫學院中醫學系學士班中醫針灸學科;中國附醫中醫針灸科
Date:	2004
Issue Date:	2009-08-20 17:58:47 (UTC+8)
Abstract:	If acupuncture is able to prevent hypertrophy of the heart, it could therefore prevent the heart from overloading and thus prevent heart failure or sudden death. We therefore studied the effects of acupuncture on blood pressure and cardiac muscle cells. Rats with spontaneous hypertension were divided into three acupuncture treatment groups and one non-treatment group. The treatment groups were classified as sham acupoint, Yanglingquan (GB. 34) and Quchi (LI. 11) groups. The measurements recorded included changes in tail pressure, femoral arterial pressure, left ventricular weight (LVW), whole heart weight (WHW), body weight (BW), LVW/BW and WHW/BW ratios and the size of the cardiac muscle cells. The results showed that femoral arterial pressure of subjects which were needled on the selected points for 3 days dropped. Acupuncture at these two acupoints seemed to improve the condition of hypertension in a short period of time. Significant changes in the femoral arterial pressure were observed in all subjects when they were treated for 6 days. In the two acupoint groups, the LVW/BW and the WHW/BW ratios did not change significantly. Cardiac muscle cells reduced in size in the Yanglingquan (GB. 34) treatment groups. This indicates that the Yanglingquan (GB. 34) points not only can lower blood pressure, but also prevent hypertrophy of cardiac muscle cells in spontaneous hypertensive rats (SHR). Therefore, acupuncture could be a good treatment modality for hypertension and hypertrophy of the heart.
Relation:	ACUPUNCTURE & ELECTRO-THERAPEUTICS RESEARCH 29(1-2):83~95
Appears in Collections:	[School of Chinese Medicine] Journal articles

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