Single dose pharmacokinetic study of lithium in Taiwanese/Chinese bipolar patients

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Title:	Single dose pharmacokinetic study of lithium in Taiwanese/Chinese bipolar patients
Authors:	Lee, CF;Yang, YY;Hu, OYP
Contributors:	附設醫院精神醫學部;Chang Gung Mem Hosp, Dept Psychiat, Tao Yuan, Taiwan;Chang Gung Coll Med & Technol, Tao Yuan, Taiwan;China Med Coll Hosp, Dept Psychiat, Taichung, Taiwan;Natl Def Med Ctr, Sch Pharm, Taipei, Taiwan
Date:	1998
Issue Date:	2010-09-24 14:51:59 (UTC+8)
Publisher:	BLACKWELL SCIENCE
Abstract:	In this study, we investigated the sedative effect of Cistanche deserticola Ma. (CD) on hexobarbital-induced sleeping time in mice and spontaneous motor activity by using automated activity meter in rats. It was found that crude extract of CD could prolong the hexobarbital-induced sleeping time and reduce spontaneous motor activity, including horizontal activity, ambulatory time and total distance. Then the water fraction of CD extract could prolong the hexobarbital-induced sleeping time and reduce the spontaneous motor activity more than that of the other fraction of CD extract in rats. These results suggest that CD ethanol extract and its water fraction possessed the sedative effect. (C) 1998 Elsevier Science Ireland Ltd.
Relation:	AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY 32(1):133-136
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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