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http://ir.cmu.edu.tw/ir/handle/310903500/30170
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| 題名: | Null type of glutathione S-transferase M1 polymorphism is associated with early onset pterygium |
| 作者: | Tsai, YY;Lee, H;Tseng, SH;Cheng, YW;Tsai, CH;Wu, YH;Tsai, FJ |
| 貢獻者: | 附設醫院眼科部;China Med Univ Hosp, Dept Ophthalmol, Taichung, Taiwan;China Med Univ Hosp, Dept Med Genet, Taichung, Taiwan;China Med Univ Hosp, Coll Chinese Med, Taichung, Taiwan;Chang Shan Med Univ, Inst Med, Taichung, Taiwan;Chang Shan Med Univ, Inst Toxicol, Taichung, Taiwan;Natl Cheng Kung Univ Hosp, Dept Ophthalmol, Tainan, Taiwan;Taichung Healthcare & Management Univ, Taichung, Taiwan |
| 日期: | 2004 |
| 上傳時間: | 2010-09-24 14:50:30 (UTC+8) |
| 出版者: | MOLECULAR VISION |
| 摘要: | Purpose: To investigate the incidence and the main pre-operative risk factors for the development of acute renal failure (ARF) in triple vessels coronary artery bypass grafting (CABG) with special reference to a subset of patients with poor cardiac function (ejection fraction <50%). Patients: The study included the patients (n = 66) requiring CABG from January 1, 1995 to January 1, 2002 in a medical center. Results: A high percentage (84.8%) of patients developed ARF and 57.6% of patients received hemodialysis (HD). Preoperative variables significantly associated with the development of ARF included increased age, increased preoperative serum creatinine, decreased preoperative 24-hour urine output and accepted emergent CABG. By the logistic multivariate regression model, increased age (OR = 1.16), preoperative serum creatinine (OR = 3.58,), decreased preoperative 24-hour urine amount (OR = 0.99,) and emergent CABG (OR = 2.01) were independently associated with ARE As for the need for HD, those factors including, preoperative serum creatinine (2.11 +/- 1.13 v 3.08 +/- 1.67mg/dL) and preoperative 24-hour urine output (1358.6 +/- 745.9 v 755.2 +/- 572.1mL/day) were significantly associated with requirement of dialysis. Using multivariate logistic regression, the significant risk factors independently associated with dialysis were preoperative serum creatinine (OR = 1.34) and preoperative 24-hour urine output (OR = 0.99). Patients with non-oliguric renal failure had significantly greater chance of recovering their renal function after cardiac surgery compared to those with oliguria (36.9% v 10.0%, P < .05). Conclusion: Preoperative 24-hour urine amount and pre-operative serum creatinine can provide valuable information for predicting the likelihood of developing acute renal failure and requiring dialysis in this subgroup of patients. (C) 2004 Elsevier Inc. All rights reserved. |
| 關聯: | MOLECULAR VISION 10(57-60):458-461 |
| 顯示於類別: | [台中附設醫院] 期刊論文
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