Pediatric endogenous endophthalmitis

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Title:	Pediatric endogenous endophthalmitis
Authors:	Tsai, YY;Tseng, SH
Contributors:	附設醫院眼科部;China Med Coll Hosp, Dept Ophthalmol, Taichung, Taiwan;Natl Cheng Kung Univ Hosp, Dept Ophthalmol, Tainan 70428, Taiwan
Date:	2000
Issue Date:	2010-09-24 14:49:58 (UTC+8)
Publisher:	EXCERPTA MEDICA ASIA LTD
Abstract:	Recent studies have shown that a C825T polymorphism of the gene encoding the G protein beta 3 subunit contributes to the genesis of essential hypertension. However, the link between the gene and blood pressure is not consistently found in different populations. The aim of the present study is to investigate this issue in Taiwan. We analyzed the allelic status in 302 hypertensive (age, 60+/-11 years; male/female, 136/166) and 199 normotensive subjects (62+/-15 years; male/female, 90/109). Our result showed that the T allelic was more frequently seen in the hypertensive group than the normotensive, but the difference did not reach statistic significance (56.5 vs. 54.3%, P>0.1). Subsequent analysis demonstrated a similar trend in the female (58.7 vs. 53.7%, P>0.1) but a reverse trend in the male (53.7 vs. 55%, P>0.1). Another finding was that the T allele frequency in all the groups was over 50%, markedly higher than those reported in whites. In conclusion, the observation suggests that the polymorphism in the G protein gene is not likely to play an important role in the manifestation of high blood pressure in Taiwan. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
Relation:	JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION 99(5):435-437
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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