Short course of prophylactic antibiotics in laparoscopically assisted vaginal hysterectomy

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Title:	Short course of prophylactic antibiotics in laparoscopically assisted vaginal hysterectomy
Authors:	Chang, WC;Hung, YC;Li, TC;Yang, TC;Chen, HY;Lin, CC
Contributors:	附設醫院婦產部;China Med Univ Hosp, Dept Obstet & Gynecol, Taichung 404, Taiwan;China Med Univ Hosp, Dept Family Med, Taichung 404, Taiwan;China Med Univ, Dept Publ Hlth, Taichung, Taiwan
Date:	2005
Issue Date:	2010-09-24 14:49:40 (UTC+8)
Publisher:	SCI PRINTERS & PUBL INC
Abstract:	Objective: To evaluate sperm DNA fragmentation in correlation with sperm parameters and IVF/intracytoplasmic sperm injection (ICSI) outcomes. Design: Retrospective review. Setting: A tertiary infertility referral clinic. Patient(s): We collected 303 semen samples from patients undergoing IVF with or without ICSI. Intervention(S): Terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate-biotin nick end labeling (TUNEL) assay, measurement of fertilization rates, good embryo rates, and pregnancy rates for the IVF/ICSI program. Main Outcome Measure(s): The percentage of sperm with DNA fragmentation, correlated with semen analysis parameters and IVF/ICSI outcomes. Result(s): Sperm DNA fragmentation rates were significantly higher in patients with abnormal sperm parameters than in those with normal sperm parameters. When sperm DNA fragmentation was > 10%, fertilization rates were affected. Sperm DNA fragmentation rates were negatively correlated with sperm velocity parameters but did not affect pregnancy outcomes. Conclusion(s): The results indicated that sperm DNA fragmentation affects fertilization rates and sperm motility but might not affect pregnancy rates. (c) 2005 by American Society for Reproductive Medicine.
Relation:	JOURNAL OF REPRODUCTIVE MEDICINE 50(7):524-528
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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