The effects of vitamin E on arylamine N-acetyltransferase activity in strains of Helicobacter pylori from peptic ulcer patients

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Title:	The effects of vitamin E on arylamine N-acetyltransferase activity in strains of Helicobacter pylori from peptic ulcer patients
Authors:	Chung, JG
Contributors:	醫學院醫學系;China Med Coll, Dept Med, Taichung 400, Taiwan
Date:	1999
Issue Date:	2010-09-24 14:49:09 (UTC+8)
Publisher:	PERGAMON-ELSEVIER SCIENCE LTD
Abstract:	BACKGROUND: Thoracopelvic dysplasia, a variant of asphyxiating thoracic dysplasia (Jeune syndrome), is an uncommon skeletal disorder characterized by a small thorax, pelvic abnormalities and other complex, combined anomalies, including hypomelia, polydactyly and renal anomalies. CASE: A 32-year-old woman, gravida 1, para 0, was referred at 27 weeks' gestation due to polyhydramnios. Sonography revealed hydramnios, low fetal thoracic circumference (TC) and abdominal circumference (AC) ratio (0.78), skull and skin edema, increased nuchal translucency (7 mm), micrognathia, low-set ears, left cardiac deviation (66 degrees), overriding fingers, and club and rock-buttock feet, Amniocentesis revealed a normal karyotype (46,XY). Asphyxiating thoracic dysplasia was considered. At 40 weeks' gestation, a male infant was delivered vaginally. Besides the prenatal findings, cryptorchidism and high-arched palate were noted. Radiography of the infant revealed a narrow, funnel-shaped thorax and small pelvis with short, flared iliac bones; poorly developed acetabulum; and small, shallow sciatic notch. No dyspnea was observed at five months postpartum. CONCLUSION: Thoracopelvic dysplasia should be considered when a low TC/AC ratio (< 0.8) is observed. In this case the final diagnosis was made after detailed exclusion of other disorders combined with observation of a small thorax. Prenatal diagnosis of thoracopelvic dysplasia is possible.
Relation:	FOOD AND CHEMICAL TOXICOLOGY 37(6):655-661
Appears in Collections:	[School of Medicine] Journal articles

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