Cryopreservation of human spermatozoa within human or mouse empty zona pellucidae

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Title:	Cryopreservation of human spermatozoa within human or mouse empty zona pellucidae
Authors:	Hsieh, YY;Tsai, HD;Chang, CC;Lo, HY
Contributors:	附設醫院婦產部;China Med Coll Hosp, Dept Obstet & Gynecol, Taichung, Taiwan
Date:	2000
Issue Date:	2010-09-24 14:47:56 (UTC+8)
Publisher:	ELSEVIER SCIENCE INC
Abstract:	Objective: To compare the effect of a single low-dose leuprolide acetate depot (LA depot) and leuprolide acetate (LA) on pituitary down-regulation in women undergoing controlled ovarian hyperstimulation (COH). Design: Retrospective study. Setting: An IVF unit of an academic medical center. Patient(s): Women who underwent COH and IVF-ET. Intervention(s): Pituitary down-regulation with half-dose LA depot (1.88 mg sc, group 1) or LA (0.5 mg/d sc, group 2) was started on menstrual days 21-23. Main Outcome Measure(s): The concentrations of estradiol (E-2), FSH, LH, gonadotropin dosages, the numbers of oocytes retrieved, oocytes fertilized and embryos transferred, and pregnancy rates of the two groups were compared. Result(s): A total of 289 patients in group 1 and 158 in group 2 were included. There were no statistically significant differences between the two groups in baseline concentrations of E-2 and FSH, concentrations of E-2, FSH, and LH during hCG administration, gonadotropin dosage, the number of oocytes retrieved, the number of oocytes fertilized and embryos transferred, and pregnancy rates. Conclusion(s): Single half-dose LA depot offers a useful alternative for pituitary suppression in ovarian stimulation for IVF. (C) 2000 by American Society for Reproductive Medicine.
Relation:	FERTILITY AND STERILITY 73(4):694-698
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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