Prenatal sonographic diagnosis of Cantrell's pentalogy with cystic hygroma in the first trimester

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Title:	Prenatal sonographic diagnosis of Cantrell's pentalogy with cystic hygroma in the first trimester
Authors:	Hsieh, YY;Lee, CC;Chang, CC;Tsai, HD;Hsu, TY;Tsai, CH
Contributors:	附設醫院婦產部;China Med Coll Hosp, Dept Obstet & Gynecol, Taichung, Taiwan;China Med Coll Hosp, Dept Pediat, Taichung, Taiwan
Date:	1998
Issue Date:	2010-09-24 14:46:53 (UTC+8)
Publisher:	JOHN WILEY & SONS INC
Abstract:	Diallyl sulfide (DAS) and diallyl disulfide (DADS). major components of garlic, were used to determine inhibition of arylamine N-acetyltransferase (NAT) activity in a human colon tumour (adenocarcinoma) cell line. Two assay Systems were performed, one with cellular cytosols (9000 g supernatant), the other with intact bacterial cell suspensions. The NAT activity in a human colon tumour cell line was inhibited by DAS and DADS in a dose-dependent manner in both system: that is, the greater the concentration of DAS and DADS in the reaction, the greater the inhibition of NAT activities in both systems. The data also indicated that DAS and DADS decrease the apparent values of K-m and V-max of NAT enzymes from human colon tumour cells in both systems examined. This is the first report to demonstrate that garlic components do affect human colon tumour cell NAT activity. (C) 1998 Elsevier Science Ltd. All rights reserved.
Relation:	JOURNAL OF CLINICAL ULTRASOUND 26(8):409-412
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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