The effects of Fructus Schisandrae (Schizandra Chinensis. (FS) on cycloheximide (CMX)-induced amnesia by using a passive avoidance task were studied in rats, FS at 0.25 and 0.75 g/kg administered for 1 week significantly prolonged the CXM-shortened step-through latency (STL). Of the fractions (n-hexane, chloroform and water), only the water fraction at 25 mg/kg administered for 1 week prolonged the CXM-shortened STL. These results suggest that the water fraction is the main active fraction of FS. Copyright (C) 1999 John Whey & Sons, Ltd.
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JOURNAL OF BIOMEDICAL MATERIALS RESEARCH 46(2):253-261
