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| 題名: | Decrease of anesthetics activity by electroacupuncture on Jen-Chung point in rabbits |
| 作者: | Chang, CL;Lee, JC;Tseng, CC;Chang, YH;Cheng, JT |
| 貢獻者: | 附設醫院針灸科;NATL CHENG KUNG UNIV,COLL MED,DEPT ANESTHESIOL,TAINAN 70101,TAIWAN;NATL CHENG KUNG UNIV,COLL MED,DEPT PHARMACOL,TAINAN 70101,TAIWAN;CHINA MED COLL HOSP,DEPT ACUPUNCTURE,TAICHUNG,TAIWAN |
| 日期: | 1995 |
| 上傳時間: | 2010-09-24 14:44:04 (UTC+8) |
| 出版者: | ELSEVIER SCI IRELAND LTD |
| 摘要: | A total of 100 women undergoing ovarian stimulation with gonadotrophin-releasing hormone agonist (GnRHa) and a human menopausal gonadotrophin (HMG)for in-vitro fertilization (IVF) participated in this randomized comparative study, Leuprolide acetate at a dose of 0.5 mg/day s.c. (n = 52, group I), or low-dose leuprolide acetate depot at a dose of 1.88 mg s.c. (n = 48, group II), was started on days 21-23 of the cycle, Stimulation with 225 IU/day HMG was started after pituitary desensitization had been achieved, The luteal phase was supported by human chorionic gonadotrophin (HCG) i.m. injection. There were no statistical differences in baseline oestradiol (24.5 +/- 4.8 versus 21.9 +/- 4.5 pg/ml)and follicle stimulating hormone (FSH) concentrations (3.9 +/- 1.9 versus 3.2 + 1.8 mIU/ml), and concentrations on the day of HCG administration of oestradiol (1657 +/- 245 versus 1512 + 165 pg/ml), luteinizing hormone (LH; 6.2 +/- 4.8 versus 5.6 +/- 4.3 mIU/ml) and FSH (10.6 +/- 2.8 versus 10.8 +/- 3.6 mIU/ml), There were also no statistical differences in the HMG dosage (26.8 +/- 1.8 versus 28.5 +/- 1.5), the number of oocytes retrieved (7.6 +/- 3.0 versus 8.1 +/- 4.3), the number of oocytes fertilized (5.3 +/- 2.1 versus 5.6 +/- 3.0) and the number of embryos transferred (3.5 +/- 1.3 versus 3.4 +/- 1.6). There was no evidence of a premature LE surge in either group, but two patients appeared to have a poor response in the leuprolide acetate group (group I), There were 11 pregnancies (21.2%) after the use of leuprolide acetate and 12 pregnancies (25.0%) in those given leuprolide acetate depot; no statistical difference existed between these two groups, Thus, an s.c. low-dose leuprolide acetate depot injection may offer a useful alternative for pituitary suppression in ovarian stimulation for IVF. |
| 關聯: | NEUROSCIENCE LETTERS 202(1月2日):93-96 |
| 顯示於類別: | [台中附設醫院] 期刊論文
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