Signet-ring cell carcinoma of the breast

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 台中附設醫院 > 期刊論文 > Item 310903500/29763

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题名:	Signet-ring cell carcinoma of the breast
作者:	Liu, SM;Chen, DR
贡献者:	附設醫院病理部;China Med Coll Hosp, Dept Pathol, Taichung, Taiwan;China Med Coll Hosp, Dept Surg, Taichung, Taiwan;China Med Coll, Taichung, Taiwan
日期:	2000
上传时间:	2010-09-24 14:42:08 (UTC+8)
出版者:	BLACKWELL SCIENCE ASIA
摘要:	In this study we investigated inhibition of Arylamine N-acetyltransferase (NAT) activity in rat blood and liver tissue cytosols by luteolin. Using high-performance liquid chromatography, NAT activity for acetylation of 2-aminofluorene and remaining unacetylated 2-aminofluorene were examined. The NAT activity in rat blood and liver tissue was inhibited by luteolin in a dose-dependent manner: higher concentrations of luteolin in the reaction resulted in greater inhibition of NAT activities in both examined tissues. The data also indicated that luteolin decreased apparent Km and Vmax of NAT enzymes from rat blood and liver tissue cytosols. This report is the first demonstration that luteolin can affect rat blood and liver tissue NAT activity.
關聯:	PATHOLOGY INTERNATIONAL 50(1):67-70
显示于类别:	[台中附設醫院] 期刊論文

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