Signet-ring cell carcinoma of the breast

CMUR > China Medical University Hospital > Jurnal articles > Item 310903500/29763

Please use this identifier to cite or link to this item: http://ir.cmu.edu.tw/ir/handle/310903500/29763

Title:	Signet-ring cell carcinoma of the breast
Authors:	Liu, SM;Chen, DR
Contributors:	附設醫院病理部;China Med Coll Hosp, Dept Pathol, Taichung, Taiwan;China Med Coll Hosp, Dept Surg, Taichung, Taiwan;China Med Coll, Taichung, Taiwan
Date:	2000
Issue Date:	2010-09-24 14:42:08 (UTC+8)
Publisher:	BLACKWELL SCIENCE ASIA
Abstract:	In this study we investigated inhibition of Arylamine N-acetyltransferase (NAT) activity in rat blood and liver tissue cytosols by luteolin. Using high-performance liquid chromatography, NAT activity for acetylation of 2-aminofluorene and remaining unacetylated 2-aminofluorene were examined. The NAT activity in rat blood and liver tissue was inhibited by luteolin in a dose-dependent manner: higher concentrations of luteolin in the reaction resulted in greater inhibition of NAT activities in both examined tissues. The data also indicated that luteolin decreased apparent Km and Vmax of NAT enzymes from rat blood and liver tissue cytosols. This report is the first demonstration that luteolin can affect rat blood and liver tissue NAT activity.
Relation:	PATHOLOGY INTERNATIONAL 50(1):67-70
Appears in Collections:	[China Medical University Hospital] Jurnal articles

Files in This Item:

There are no files associated with this item.