Comparison between technetium-99m hexamethylpropyleneamineoxide labeled white blood cell abdomen scan and abdominal sonography to detect appendicitis in female patients with an atypical clinical presentation

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Title:	Comparison between technetium-99m hexamethylpropyleneamineoxide labeled white blood cell abdomen scan and abdominal sonography to detect appendicitis in female patients with an atypical clinical presentation
Authors:	Cheng, KS;Shiau, YC;Lin, CC;Lee, CC;Kao, A
Contributors:	附設醫院核子醫學部;China Med Coll Hosp, Dept Nucl Med, Div Gastroenterol, Taichung 404, Taiwan;China Med Coll Hosp, Dept Family Med, Div Gastroenterol, Taichung 404, Taiwan;China Med Coll Hosp, Dept Med Res, Div Gastroenterol, Taichung 404, Taiwan;Natl Taiwan Univ, Coll Elect Engn, Inst Biomed Engn, Taipei 10764, Taiwan;Natl Taiwan Univ, Far Eastern Mem Hosp, Dept Nucl Med, Taipei 10764, Taiwan
Date:	2003
Issue Date:	2010-09-24 14:41:26 (UTC+8)
Publisher:	H G E UPDATE MEDICAL PUBLISHING S A
Abstract:	Background/Aims: Although antidepressants have been used for decades in treating patients with functional abdominal syndromes, how they influence gastrointestinal motility remains unclear. We aimed to assess the role of depression in functional dyspepsia, and the effect of antidepressants on the functional dyspepsia patients' symptoms and gastric myoelectrical activity. Methodology: We conducted an open clinical trial with 40 functional dyspepsia patients. Zung self-rating depression scale was used in evaluating the patients' depression. Cutaneous electrogastrography and evaluation of upper gastrointestinal symptoms were performed before and after administration of a one-month course of fluoxetine. Results: In the baseline study, the depressed functional dyspepsia patients had higher symptom scores than non-depressed patients (P<0.05). The depressed functional dyspepsia patients had higher percentages of tachygastria than healthy controls (P<0.05), but the electrogastrography parameters of depressed and non-depressed functional dyspepsia patients were not different. After one-month fluoxetine treatment, the symptom scores improved significantly in the depressed functional dyspepsia patients (P<0.05), but not in the non-depressed patients. Electrogastrography did not improve in either group. Conclusions: Depressive functional dyspepsia patients had higher symptom scores and responded well to fluoxetine treatment. However, electrogastrography did not improve after the treatment. These findings suggest that depression is significant in the presentation of functional dyspepsia symptoms, but not correlated with gastric myoelectrical activity.
Relation:	HEPATO-GASTROENTEROLOGY 50(49):136-139
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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