Using non-invasive radionuclide imaging to detect esophagitis in patients with gastroesophageal reflux disease

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Title:	Using non-invasive radionuclide imaging to detect esophagitis in patients with gastroesophageal reflux disease
Authors:	Hsu, CH;Shiun, SC;Hsu, NY;Sun, SS;Kao, A;Lee, CC;Lin, CC
Contributors:	附設醫院核子醫學部;China Med Coll Hosp, Dept Nucl Med, Taichung 404, Taiwan;China Med Coll Hosp, Dept Med Res, Taichung 404, Taiwan;China Med Coll Hosp, Dept Family Med, Taichung 404, Taiwan;China Med Coll Hosp, Div Gastroenterol, Taichung 404, Taiwan;China Med Coll Hosp, Div Chest Surg, Taichung 404, Taiwan
Date:	2003
Issue Date:	2010-09-24 14:41:23 (UTC+8)
Publisher:	H G E UPDATE MEDICAL PUBLISHING S A
Abstract:	Background/Aims: Acute appendicitis is a clinically challenging surgical disease which is particularly difficult to diagnosis in women. An atypical presentation is a major obstacle to quickly diagnose acute appendicitis. Methodology: Fifty female patients with acute abdomen pain who were suspected of having appendicitis, but who had atypical findings were included in this study. After an intravenous injection of technetium-99m hexamethylpropyleneamineoxide (Tc99m HMPAO) labeled white blood cells, serial anterior abdomen-pelvis images at 30min, 60min, 120min and 240min were obtained using a gamma camera. Meanwhile,. at the point of maximal tenderness, abdominal sonography was performed with a graded compression technique for both longitudinal and transverse images. Results: Thirty-two patients received a laparotomy for surgical and pathological diagnoses. The remaining 18 patients did not receive operations and showed no evidence of appendicitis after at least a one-month follow-up period. Two patients had false-positive white blood cell scan findings and 2 patients had false-negative white blood cell scan findings. The overall sensitivity, specificity, and accuracy for white blood cell scans in diagnosing appendicitis was 93.3%, 90.0%, 92.0%, respectively. One patient had false-positive abdominal sonographic finding and 5 patients had false-negative abdominal sonographic findings. The overall sensitivity, specificity, and accuracy for abdominal sonography scans in diagnosing appendicitis were 83.3%, 95.0%, and 88.0%, respectively. Conclusions: The Tc-99m HMPAO white blood cell scan provides a more sensitive and accurate method for the diagnosis of appendicitis in female patients with equivocal clinical presentation when compared with abdominal sonography.
Relation:	HEPATO-GASTROENTEROLOGY 50(49):107-109
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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