Effect of P-glycoprotein and multidrug resistance associated protein gene expression on Tc-99m MIBI imaging in hepatocellular carcinoma

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Title:	Effect of P-glycoprotein and multidrug resistance associated protein gene expression on Tc-99m MIBI imaging in hepatocellular carcinoma
Authors:	Chang, CS;Huang, WT;Yang, SS;Yeh, HZ;Kao, CH;Chen, GH
Contributors:	附設醫院核子醫學部;Taichung Vet Gen Hosp, Div Gastroenterol, Taichung, Taiwan;Chung Shan Med Univ, Dept Internal Med, Taichung, Taiwan;Yuanpei Inst Sci & Technol, Dept Radiol Technol, Taichung, Taiwan;Natl Young Min Med Univ, Dept Internal Med, Taipei, Taiwan;China Med Coll Hosp, Dept Nucl Med, Taichung, Taiwan
Date:	2003
Issue Date:	2010-09-24 14:41:13 (UTC+8)
Publisher:	ELSEVIER SCIENCE INC
Abstract:	Tubulopapillary hidradenoma (TPH)(1) is a term proposed to describe morphological dermal ductal tumors with both eccrine and apocrine differentiation. The term TPH encompasses a spectrum of lesions that includes tubular apocrine adenoma (TAA) and papillary eccrine adenoma (PEA):(2) PEA and TAA can be indistinguishable both clinically and histologically. We described a case of TPH with both prominent eccrine and apocrine differentiation combined with syringocystadenoma papilliferum (SCAP) over the distal extremity. This rarely encountered dermatopathological phenomenon is the sixth reported case from the literature in which PEA or TAA and SCAP were present in the same lesion.(3-7) Furthermore, the tumor had a warty surface, which is histologically consistent with a typical viral verruca. Although PCR and DNA probe hybridization for human papilloma virus (HPV) types 2, 6/11, 16 and 18 failed to reveal positive results, the location and clinicopathologic correlation convinced us that superimposed HPV could not be excluded.
Relation:	NUCLEAR MEDICINE AND BIOLOGY 30(2):111-117
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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