A higher prevalence of abnormal regional cerebral blood flow in patients with syndrome X and abnormal myocardial perfusion

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Title:	A higher prevalence of abnormal regional cerebral blood flow in patients with syndrome X and abnormal myocardial perfusion
Authors:	Pai, PY;Liu, FY;Kao, A;Lin, CC;Lee, CC
Contributors:	附設醫院核子醫學部;China Med Coll Hosp, Dept Nucl Med, Taichung 404, Taiwan;China Med Coll Hosp, Dept Med Res, Taichung 404, Taiwan;China Med Coll Hosp, Dept Family Med, Taichung 404, Taiwan;China Med Coll Hosp, Dept Neurol, Taichung 404, Taiwan;China Med Coll Hosp, Div Cardiol, Taichung 404, Taiwan;Far Eastern Mem Hosp, Dept Nucl Med, Taipei, Taiwan
Date:	2003
Issue Date:	2010-09-24 14:40:49 (UTC+8)
Publisher:	JAPAN HEART JOURNAL, SECOND DEPT OF INTERNAL MED
Abstract:	Syndrome X is used to describe patients with chest pain and a normal coronary angiogram. We reviewed technetium-99m tetrofosmin (Tc-99m TF) myocardial perfusion single photon emission computed tomography (SPECT) results and clinical data of 43 syndrome X patients and 30 healthy controls with normal left ventricular ejection fraction and no cardiac abnormalities. The Tc-99m TF myocardial perfusion SPECT results showed 12 (27.9%) syndrome X patients had normal myocardial perfusion and 31 (72.1%) had abnormal myocardial perfusion, including 6 (14.0%) patients with fixed defects, 20 (46.5%) patients with transient defects, and 5 (11.6%) patients with reverse defects. The results of exercise ECG were not related to perfusion defects in Tc-99m TF myocardial perfusion SPECT. In contrast, all of the 30 (100.0%) healthy controls had normal myocardial perfusion SPECT results. We conclude that abnormal Tc-99m TF myocardial perfusion SPECT is common in syndrome X and does not correlate well with the exercise ECG. However, further studies with larger case numbers and long term follow up in patients with myocardial events are necessary to support our findings.
Relation:	JAPANESE HEART JOURNAL 44(2):145-152
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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