Detection of recurrent nasopharyngeal carcinomas after radiotherapy with technetium-99m tetrofosmin single photon emission computed tomography in patients with indeterminate magnetic resonance imaging findings

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Title:	Detection of recurrent nasopharyngeal carcinomas after radiotherapy with technetium-99m tetrofosmin single photon emission computed tomography in patients with indeterminate magnetic resonance imaging findings
Authors:	Weng, YC;Yen, RF;Tsai, MH;Wang, JJ;Ho, ST;Kao, CH
Contributors:	附設醫院核子醫學部;China Med Univ Hosp, Dept Nucl Med, Taichung, Taiwan;China Med Univ Hosp, Dept Otolaryngol, Taichung, Taiwan;Taichung Vet Gen Hosp, Dept Radiat Oncol, Taichung, Taiwan;Natl Taiwan Univ Hosp, Dept Nucl Med, Taipei, Taiwan;Chie Mei Med Ctr, Dept Med Res, Tainan, Taiwan;Natl Def Med Ctr, Sch Med, Taipei, Taiwan
Date:	2003
Issue Date:	2010-09-24 14:39:55 (UTC+8)
Publisher:	MARCEL DEKKER INC
Abstract:	Thallium-201 (Tl-201) is a recognized tumor-imaging agent; however, the usefulness of Tl-201 in prostate cancer has not been studied. The purpose of this preliminary study was to evaluate the efficacy of Tl-201 single-photon emission computed tomography (SPECT) imaging for differentiating prostate cancer from benign prostatic hyperplasia (BPH). Methods: Tl-201 pelvic SPECT was performed in 10 patients (aged 64-78 years) with biopsy-proven BPH before transurethral resection of the prostate and 15 patients (aged 65-81 years) with biopsy-proven prostate cancer prior to any therapeutic modality or invasive surgical procedures for treatment of their prostate cancer. Results: From the 15 patients with prostate cancer, Tl-201 pelvic SPECT detected prostate cancer in 13 (86.7%) but not in 2 (13.3%) patients with Gleason scores of 5 (2 + 3). In contrast, all 10 patients with BPH (100.0%) had negative results of Tl-201 pelvic SPECT. Conclusion: Our study showed that Tl-201 pelvic SPECT scan is very helpful in distinguishing between prostate cancer and BPH.
Relation:	CANCER INVESTIGATION 21(5):695-700
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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