Impaired salivary function in patients with noninsulin-dependent diabetes mellitus with xerostomia

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Title:	Impaired salivary function in patients with noninsulin-dependent diabetes mellitus with xerostomia
Authors:	Lin, CC;Sun, SS;Kao, A;Lee, CC
Contributors:	附設醫院核子醫學部;China Med Coll Hosp, Dept Nucl Med, Taichung 404, Taiwan;China Med Coll Hosp, Dept Family Med, Taichung 404, Taiwan;China Med Coll Hosp, Dept Med Res, Taichung 404, Taiwan
Date:	2002
Issue Date:	2010-09-24 14:39:18 (UTC+8)
Publisher:	ELSEVIER SCIENCE INC
Abstract:	The adenine/cytosine(1166) (A/C-1166) polymorphism of the angiotensin-II type 1 receptor (AGTR1) gene is presumed to be associated with mitral valve prolapse syndrome (MVPS) in Caucasians. To investigate whether a similar association exists among the Chinese population in Taiwan, 100 patients with MVP diagnosed by echocardiography and 100 normal subjects were studied by polymerase chain reaction-based restriction analysis. The difference in genotype (chi(2)=0.24; p=0.89) and allelic (Yates' chi(2)=0.06; p=0.81) frequencies between the groups were not significant. Further categorization of the MVP patients into mild and severe subgroups also revealed no statistical difference from the controls. It was concluded that A/C-1166 polymorphism of the AGTR1 gene is not a suitable genetic marker of MVPS in Taiwan Chinese.
Relation:	JOURNAL OF DIABETES AND ITS COMPLICATIONS 16(2):176-179
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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