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題名: | Uptake of Tc-99m tetrofosmin in lymphoma cell lines: a comparative study with Tc-99m sestamibi |
作者: | Ding, HJ;Shiau, YC;Tsai, SC;Wang, JH;Ho, ST;Kao, A |
貢獻者: | 附設醫院核子醫學部;China Med Coll Hosp, Dept Nucl Med, Taichung 404, Taiwan;China Med Coll Hosp, Dept Med Res, Taichung 404, Taiwan;Kaohsiung Med Univ, Sch Technol Med Sci, Dept Med Res, Kaohsiung, Taiwan;Natl Taiwan Univ, Far Eastern Mem Hosp, Dept Nucl Med, Taipei 10764, Taiwan;Natl Taiwan Univ, Coll Elect Engn, Inst Biomed Engn, Taipei 10764, Taiwan;Show Chwan Mem Hosp, Dept Nucl Med, Changsha, Peoples R China;Chi Mei Med Ctr, Dept Med Res, Tainan, Taiwan;Natl Def Med Ctr, Sch Med, Taipei, Taiwan |
日期: | 2002 |
上傳時間: | 2010-09-24 14:38:58 (UTC+8) |
出版者: | PERGAMON-ELSEVIER SCIENCE LTD |
摘要: | Technetium-99m ethyl cysteinate dimer (Tc-99m ECD) brain single photon emission computed tomography (SPECT) was used to detect abnormal regional cerebral blood flow (rCBF) in primary antiphospholipid antibody syndrome (PAPS) patients. The patients had mild neuropsychiatric manifestations and normal brain magnetic resonance imaging (MRI) findings in this preliminary study. Fifteen such female PAPS patients were examined with Tc-99m ECD brain SPECT in order to evaluate the rCBF. In addition, serum anti-cardiolipin antibodies (ACA) and lupus anticoagulant (LA) were simultaneously measured for comparison. Results: (a) Tc-99m ECD brain SPECT revealed hypoperfusion brain lesions in 12 (80%) of the PAPS patients. Pariental lobes were the most commonly involved areas. (b) 11 (73%) and 9 (60%) cases had positive ACA and positive LA, respectively. In addition, ACA and LA results were correlated to the Tc-99m ECD brain SPECT findings. Tc-99m ECD brain SPECT is a sensitive tool for detecting abnormal rCBF in PAPS patients with mild neuropsychiatric manifestations and normal brain MRI findings. |
關聯: | APPLIED RADIATION AND ISOTOPES 56(6):853-856 |
顯示於類別: | [台中附設醫院] 期刊論文
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