Technetium-99m methoxyisobutylisonitrile imaging for parathyroid adenoma: relationship to P-glycoprotein or multidrug resistance-related protein expression

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Title:	Technetium-99m methoxyisobutylisonitrile imaging for parathyroid adenoma: relationship to P-glycoprotein or multidrug resistance-related protein expression
Authors:	Kao, A;Shiau, YC;Tsai, SC;Wang, JJ;Ho, ST
Contributors:	附設醫院核子醫學部;China Med Coll Hosp, Dept Nucl Med, Taichung 404, Taiwan;China Med Coll Hosp, Dept Med Res, Taichung 404, Taiwan;Natl Taiwan Univ, Coll Elect Engn, Inst Biomed Engn, Far Eastern Mem Hosp,Dept Nucl Med, Taipei 10764, Taiwan;Show Chwan Mem Hosp, Dept Nucl Med, Chunghua, Taiwan;Chi Mei Med Ctr, Dept Med Res, Tainan, Taiwan;Natl Def Med Ctr, Sch Med, Taipei, Taiwan
Date:	2002
Issue Date:	2010-09-24 14:38:20 (UTC+8)
Publisher:	SPRINGER-VERLAG
Abstract:	Ferulic acid (50 and 10C. mg/kg) reversed the step-through latency shortened by scopolamine and cycloheximide but not by p-chloroamphetamine in an inhibitory avoidance performance. Piracetam and tacrine might reverse the step-through latency shortened by the above drugs. However, ferulic acid, piracetam or tacrine alone at any used dose did not influence motor activity produced by non-shock rats. Furthermore, the cerebral blood flow of rats treated with ferulic acid, piracetam, or tacrine was enhanced. From these results, we suggest that the potency of ferulic acid was better than that of piracetam, but its action mechanism was somewhat different from that of piracetam and tacrine. Thus, the attenuating effects of ferulic acid on the avoidance performance impairment were related to memory processes, and might be enhancing the cholinergic activities and cerebral blood circle.
Relation:	EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 29(8):1012-1015
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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