Comparison of the metabolic effects of metformin and troglitazone on fructose-induced insulin resistance in male Sprague-Dawley rats

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Title:	Comparison of the metabolic effects of metformin and troglitazone on fructose-induced insulin resistance in male Sprague-Dawley rats
Authors:	Chen, CC;Wang, HJ;Shih, HC;Sheen, LY;Chang, CT;Chen, RH;Wang, TY
Contributors:	附設醫院核子醫學部;China Med Coll Hosp, Dept Med, Div Endocrinol & Metab, Taichung, Taiwan;China Med Coll Hosp, Dept Lab Med, Taichung, Taiwan;China Med Coll, Dept Physiol, Taichung, Taiwan;China Med Coll, Dept Nutr, Taichung, Taiwan
Date:	2001
Issue Date:	2010-09-24 14:36:56 (UTC+8)
Publisher:	EXCERPTA MEDICA ASIA LTD
Abstract:	A series of 2 ' ,3 ' ,4 ' ,6,7-substituted 2-aryl quinazolinones were synthesized and evaluated for biological activity. Among them, 17 displayed significant growth inhibitory action against a panel of tumor cell lines. Compound 17 was also a potent inhibitor of tubulin polymerization. Compounds 8-10 displayed selective activity against P-gp-expressing epidermoid carcinoma of the nasopharynx. (C) 2001 Elsevier Science Ltd. all rights reserved.
Relation:	JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION 100(3):176-180
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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