Technetium-99m methoxyisobutylisonitrile chest imaging for small-cell lung cancer

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Title:	Technetium-99m methoxyisobutylisonitrile chest imaging for small-cell lung cancer
Authors:	Kao, A;Shiun, SC;Hsu, NY;Sun, SS;Lee, CC;Lin, CC
Contributors:	附設醫院核子醫學部;China Med Coll Hosp, Dept Nucl Med, Taichung 404, Taiwan;China Med Coll Hosp, Dept Chest Surg, Taichung 404, Taiwan;China Med Coll Hosp, Dept Med Res, Taichung 404, Taiwan;China Med Coll Hosp, Dept Family Med, Taichung 404, Taiwan;China Med Coll Hosp, Ctr Oncol, Taichung 404, Taiwan
Date:	2001
Issue Date:	2010-09-24 14:36:00 (UTC+8)
Publisher:	KLUWER ACADEMIC PUBL
Abstract:	Systemic administration of dl-tetrahydropalmatine (THP; 10-50 mg.kg(-1) intraperitoneally) produced a proportional decrease in both colonic temperature and release of hypothalamic serotonin (5-hydroxytryptamine (5-HT)) in rats at room temperature. The hypothermia was brought about by cutaneous vasodilation and decreased metabolism. The THP-induced hypothermia was significantly attenuated in rats with brain 5-HT depletion produced by control injection of 5,7-dihydroxytryptamine or in rats with 5-HT2A receptor activation produced by 1-(2,5-dimethoxy-4-iodophenyl) -2-aminopropane, or in rats with 5-HT1A receptor antagonist produced by (-)-pindolol. The results suggest involvement of serotoninergic antagonism in the THP-induced hypothermia in rats (C) 2001 Published by Elsevier Science Ireland Ltd.
Relation:	ANNALS OF ONCOLOGY 12(11):1561-1566
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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