Whole body positron emission tomography with 18F-fluoro-2-deoxyglucose for the detection of recurrent ovarian cancer

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Title:	Whole body positron emission tomography with 18F-fluoro-2-deoxyglucose for the detection of recurrent ovarian cancer
Authors:	Yen, RF;Sun, SS;Shen, YY;Changlai, SP;Kao, A
Contributors:	附設醫院核子醫學部;Chang Shan Med & Dent Coll Hosp, Dept Nucl Med, Taichung, Taiwan;Chang Shan Med & Dent Coll Hosp, PET Ctr, Taichung, Taiwan;Shin Kong Wu Ho Su Mem Hosp, Dept Nucl Med, Taipei, Taiwan;Shin Kong Wu Ho Su Mem Hosp, PET Ctr, Taipei, Taiwan;China Med Coll Hosp, Dept Nucl Med, Taichung, Taiwan;China Med Coll Hosp, PET Ctr, Taichung, Taiwan;Natl Taiwan Univ Hosp, PET Ctr, Taipei, Taiwan
Date:	2001
Issue Date:	2010-09-24 14:35:44 (UTC+8)
Publisher:	INT INST ANTICANCER RESEARCH
Abstract:	The aim of this study was to compare the value of technetium-99m tetrofosmin (Tc-TF) scintigraphy with that of gallium-67 citrate (Ga-67) scintigraphy for detecting malignant lymphoma. In this study, 50 patients with malignant lymphoma underwent Tc-TF and Ga-67 scintigraphy before receiving any therapy. Tc-TF scintigraphy detected malignant lymphoma in 44 (88%) patients, but was false-negative in 4 cases of infradiaphragmatic malignant lymphoma and in 2 cases of malignant lymphoma with chemotherapy resistance. Ga-67 scintigraphy detected malignant lymphoma in 45 (90%) patients, but was false-negative in 3 cases of low-grade non-Hodgkins lymphoma and in 2 cases of malignant lymphoma with bane marrow involvement. There was no significant difference in sensitivity between Tc-TF and Ga scintigraphy. However, a combination of Tc-TF and Ga-67 scintigraphy detected malignant lymphoma in all 50 patients (100%). We conclude that it is necessary to combine Tc-TF and Ga-67 scintigraphy to accurately detect malignant lymphoma.
Relation:	ANTICANCER RESEARCH 21(5):3691-3694
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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