Detection of esophageal carcinoma using single photon emission computed tomography with technetium-99m tetrofosmin

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Title:	Detection of esophageal carcinoma using single photon emission computed tomography with technetium-99m tetrofosmin
Authors:	Sun, SS;Hsieh, JF;Tsai, SC;Ho, YJ;Lee, JK;Kao, CH
Contributors:	附設醫院核子醫學部;Taichung Vet Gen Hosp, Dept Nucl Med, Taichung 407, Taiwan;China Med Coll Hosp, Dept Nucl Med, Taichung, Taiwan;Chi Mei Fdn Hosp, Dept Nucl Med, Tainan, Taiwan;Jen Ai Hosp, Dept Radiol, Taichung, Taiwan;Show Chwan Mem Hosp, Dept Nucl Med, Chunghua, Taiwan
Date:	2000
Issue Date:	2010-09-24 14:34:45 (UTC+8)
Publisher:	INT INST ANTICANCER RESEARCH
Abstract:	This study evaluated the clinical role ofTc-99m-methoxyisobtylisonitrile (Tc-MIBI) single photon emission computed tomography (SPECT) of the chest in the detection of mediastinal lymph node (MLN) metastasis inpatients with nonsmall cell lung cancer (NSCLC). Twenty-five patients with proven NSCLC were enrolled in this study. Each of the patients received computed tomography (CT) of the chest and Tc-MIBI SPECT of the chest for presurgical staging. A postsurgical pathologic diagnosis was made and these patients were evaluated for the study of mediastinal lymph nde (MLN) involvement. Meanwhile, 10 volunteers also accepted Tc MIBI SPECT of the chest for comparison. The results showed that the diagnostic sensitivity, specificity and accuracy of Tc-MIBI chest SPECT were 81.8%, 85.7% and 84% and for chest CT they are 36.3%, 85.7% and 64%, respectively. Our results indicated that Tc-MIBI chest SPECT was more sensitive and accurate than chest CT in the evaluation and detection of MLN involvement in the NSCLC patients.
Relation:	ANTICANCER RESEARCH 20(5C):3641-3645
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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