Novel peptide inhibitors for Grb2 SH2 domain and their detection by surface plasmon resonance

CMUR > College of Health Care > Graduate Institute of Nutrition > Journal articles > Item 310903500/29397

Please use this identifier to cite or link to this item: http://ir.cmu.edu.tw/ir/handle/310903500/29397

Title:	Novel peptide inhibitors for Grb2 SH2 domain and their detection by surface plasmon resonance
Authors:	Lung, FDT;Tsai, JY;Wei, SY;Cheng, JW;Chen, C;Li, P;Roller, PP
Contributors:	健康照護學院營養系;China Med Coll, Dept Nutr, Taichung 404, Taiwan;Natl Tsing Hua Univ, Dept Life Sci, Div Struct Biol & Biomed Sci, Hsinchu 300, Taiwan;Acad Sinica, Inst Biomed Sci, Tokyo 115, Japan;NCI, Frederick Canc Res & Dev Ctr, Med Chem Lab, Frederick, MD 21702 USA
Date:	2002
Issue Date:	2010-09-24 14:33:48 (UTC+8)
Publisher:	BLACKWELL MUNKSGAARD
Abstract:	Background. In Taiwan, family members care for 80-90% of disabled people, but most have no professional training or knowledge of care for the disabled. Therefore, the adequacy of care received by the disabled needs to be assessed. Aims. To evaluate the unmet nursing care needs of physically disabled patients and determine the relevant factors. Methods. All 322 subjects were over 18 years of age, had a Barthel Index of less than 80 and became disabled 2 years prior to the commencement of this study. All subjects were outpatients of hospitals in central Taiwan and were contacted by phone to schedule an interview. Based on activity of daily living (ADL) scores, patients were divided into three groups: complete dependency, severe dependency and moderate dependency. After training, nurses evaluated the patients' ADL and completed the 20-item Assessment of Nursing Activity (ANA) questionnaire. Based on the ANA, subjects' unmet needs and caregivers' knowledge requirements were assessed. Findings. The results showed the mean number of unmet needs was approximately five. Percentage of unmet needs was 44.8%. For complete dependency patients, the unmet needs score of patients and the needs score of caregiver's knowledge was highest, followed by the severe dependency group, and the moderate dependency group. Based on multiple linear regression, the factors that affected unmet need were as follows: age of patient, ADL score, education level of the caregivers, average daily duration of care and need of caregiving knowledge. Our findings indicate that the provision of counseling and educational support for family caregivers is required to promote quality of care for the disabled.
Relation:	JOURNAL OF PEPTIDE RESEARCH 60(3):143-149
Appears in Collections:	[Graduate Institute of Nutrition ] Journal articles

Files in This Item:

There are no files associated with this item.

Loading...