中國醫藥大學機構典藏 China Medical University Repository, Taiwan:Item 310903500/29393
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 29490/55136 (53%)
造访人次 : 1505881      在线人数 : 541
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    主页 ‧ 登入 ‧ 上传 ‧ 说明 ‧ 关于CMUR ‧ 管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.cmu.edu.tw/ir/handle/310903500/29393


    题名: Four anthropometric indices and cardiovascular risk factors in Taiwan
    作者: Huang, KC;Lin, WY;Lee, LT;Chen, CY;Lo, H;Hsia, HH;Liu, IL;Shau, WY;Lin, RS
    贡献者: 附設醫院家醫科;Natl Taiwan Univ Hosp, Dept Family Med, Obes Res Grp, Taipei 100, Taiwan;China Med Coll Hosp, Dept Family Med, Taichung, Taiwan;Chia Nan Univ Pharm & Sci, Hlth Care Adm, Taipei, Taiwan;Natl Taiwan Univ, Grad Inst Prevent Med, Taipei 10764, Taiwan;MJ Hlth Screening Ctr, Taipei, Taiwan
    日期: 2002
    上传时间: 2010-09-24 14:33:43 (UTC+8)
    出版者: NATURE PUBLISHING GROUP
    摘要: The purpose of this study was to determine whether IL-1 receptor antagonist (IL-1Ra) gene polymorphism is a marker of susceptibility to or severity of systemic lupus erythematosus (SLE) in Chinese patients. The study included 52 Chinese patients with SLE. One hundred and three unrelated, healthy individuals living in central Taiwan served as controls, From genomic DNA, the polymorphism of the gene for IL-1Ra was typed. Allelic frequencies and carriage rates were compared between SLE patients and controls. The relationship between allelic frequencies and clinical manifestations of SLE was evaluated. We found an increased frequency of IL1RN*2 in the SLE patients compared to normal controls (chi(2) = 4.15, P < 0.05), with an odds ratio (of allele frequency) of 2.63 (95% confidence interval 1.00-6.96). The carriage rate of IL1RN*2 was also higher in the SLE patients (6.8% in the controls vs. 17.3% in the SLE patients). We observed increased frequencies of malar rash and photosensitivity among patients with IL1RN*2 (77.8%) compared to patients without the allele (48.8%). However, this difference did not reach statistical significance (chi(2) = 2.51, P = 0.11). This study indicated that the frequency of IL1RN*2 is higher in Chinese SLE patients than in Chinese normal controls in Taiwan. However, there was no association between the frequency of IL1RN*2 and clinical manifestations.
    關聯: INTERNATIONAL JOURNAL OF OBESITY 26(8):1060-1068
    显示于类别:[台中附設醫院] 期刊論文

    文件中的档案:

    没有与此文件相关的档案.



    在CMUR中所有的数据项都受到原著作权保护.

    TAIR相关文章

     

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈