Usefulness of captopril renography to predict the benefits of renal artery revascularization or captopril treatment in hypertensive patients with diabetic nephropathy

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Title:	Usefulness of captopril renography to predict the benefits of renal artery revascularization or captopril treatment in hypertensive patients with diabetic nephropathy
Authors:	Lin, CC;Shiau, YC;Li, TC;Kao, A;Lee, CC
Contributors:	附設醫院家醫科;China Med Coll Hosp, Dept Family Med, Taichung 404, Taiwan;China Med Coll Hosp, Dept Med Res, Taichung 404, Taiwan;Natl Taiwan Univ, Far Eastern Mem Hosp, Dept Nucl Med, Taipei 10764, Taiwan;Natl Taiwan Univ, Inst Biomed Engn, Coll Elect Engn, Taipei 10764, Taiwan;China Med Coll, Inst Chinese Med, Taichung, Taiwan
Date:	2002
Issue Date:	2010-09-24 14:33:34 (UTC+8)
Publisher:	ELSEVIER SCIENCE INC
Abstract:	Non-insulin-dependent diabetes mellitus (NIDDM) is considered to predispose impaired gallbladder function and an increased prevalence of gallbladder disease. The aim of this study was to evaluate the gallbladder function of patients with NIDDM by quantitative technetium-99m-labeled imino-diacetic acid analogue (Tc-99m DISIDA) cholescintigraphy. One hundred and forty-five NIDDM patients (100 males, 45 females; age: 58.7 +/- 9.5 years) with the absence of autonomic or peripheral neuropathy and without gallbladder or liver disorders were enrolled in this study. The patients were categorized by blood sugar control (HbA(lc) greater than or equal to 10% as a poor blood sugar control group and HbA(1c) < 10% as a good blood sugar control group) and disease duration (diabetic duration &GE; 10 years as a longer-duration group and diabetic duration < 10 years as a shorter-duration group). In addition, 60 normal controls (38 males, 22 females; age: 59.1 +/- 10.2 years) were also studied for comparison. All NIDDM patients and normal controls underwent Tc-99m DISIDA cholescintigraphy, and the filling fraction (FF) and ejection fraction (EF) of gallbladder were calculated. The results showed significant difference between (1) NIDDM patients versus normal controls in FF and EF, (2) poor versus good blood sugar control of NIDDM patients in FF and EF, and (3) longer versus shorter disease duration of NIDDM patients in FF and EF. Our study, including a large number of subjects, showed that gallbladder function of patients with NIDDM is more impaired than the normal controls; and impaired gallbladder function in NIDDM patients is related to disease duration and blood sugar control. (C) 2002 Elsevier Science Inc. All rights reserved.
Relation:	JOURNAL OF DIABETES AND ITS COMPLICATIONS 16(5):344-346
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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