中國醫藥大學機構典藏 China Medical University Repository, Taiwan:Item 310903500/29370
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    題名: Emergency department response to SARS, Taiwan
    作者: Chen, WK;Wu, HDI;Lin, CC;Cheng, YC
    貢獻者: 附設醫院急診部;China Med Univ Hosp, Dept Emergency Med, Taichung 404, Taiwan;China Med Univ, Taichung, Taiwan
    日期: 2005
    上傳時間: 2010-09-24 14:33:18 (UTC+8)
    出版者: CENTER DISEASE CONTROL
    摘要: Put-pose: To assess the p53 protein expression in pterygial tissue and to review all immmunohistochemical studies on pterygium from Medline to evaluate the roles of age, gender, race, p53 antibody, cutoff levels of immunohistochemical analysis, parts of pterygium, p53 gene mutation spectrum, and primary or recurrent pterygium on the p53 staining results. Methods: lmmunohistochemical staining was performed on 127 pterygial specimens and 18 normal conjunctival samples. All 8 immunohistochemical studies on p53 expression in pterygium from Medline were reviewed. Results: Among the 127 pterygial samples, there were 29 specimens (22.8%) positive for p53 expression. There was no significant difference between the p53-positive and p53-negative groups with respect to age or gender. Conclusion: The positive rate of p53 staining in 8 immunohistochemical studies was 7.9%, 36.8%, 37.5%, 38.1%, 50%, 53.8%, 60%, and 100%, respectively. p53 protein antibody, cutoff level, race, and p53 gene mutational spectra all affect the results on the p53 staining. Different parts of pterygium and gender merit further evaluation in their role on p53 staining result.
    關聯: EMERGING INFECTIOUS DISEASES 11(7):1067-1073
    顯示於類別:[台中附設醫院] 期刊論文

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