Risk factors for gallstone disease in a hospital-based study

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 台中附設醫院 > 期刊論文 > Item 310903500/29355

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题名:	Risk factors for gallstone disease in a hospital-based study
作者:	Lai, SW;Ng, KC
贡献者:	附設醫院急診部;China Med Coll Hosp, Dept Emergency Med, Taichung 404, Taiwan;China Med Coll Hosp, Dept Community Med, Taichung 404, Taiwan
日期:	2002
上传时间:	2010-09-24 14:33:04 (UTC+8)
出版者:	SOUTHERN MEDICAL ASSN
摘要:	Flavonoids represent a major group of natural antioxidants. In recent years, flavonoids have attracted increasing interest due to their various beneficial pharmacological effects and additional abilities to modulate CYPs and P-glycoprotein (Pgp), the product of mdr (multidrug - resistance) genes. There is a very large amount of in vitro data of flavonoids, but very few reports of animal studies are available. Moreover, information concerning the biological fates of flavonoids is very limited. Therefore, whether published in vitro data are predictive of in vivo effects need further discussion. On the other hand, flavonoids may activate or inhibit CYPs and Pgp, which may be beneficial in detoxication, in chemoprevention, or in drug resistance suppression. The aim of this review is to give an overview of the research reports on the biological fates of flavonoids and their potential interactions with xenobiotics. The perspectives for future research on flavonoids in herbs will be suggested at the end of this article.
關聯:	SOUTHERN MEDICAL JOURNAL 95(12):1419-1423
显示于类别:	[台中附設醫院] 期刊論文

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