Evaluation of liver diseases via MTC and contrast agent

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Title:	Evaluation of liver diseases via MTC and contrast agent
Authors:	Chen, JH;Yeung, HN;Lee, SK;Chai, JW
Contributors:	附設醫院放射線部;China Med Coll Hosp, Dept Radiol, Taichung 404, Taiwan
Date:	1999
Issue Date:	2010-09-24 14:30:24 (UTC+8)
Publisher:	JOHN WILEY & SONS INC
Abstract:	PURPOSE: To investigate the clinical manifestations and treatment outcomes in patients with stage T4M0 nasopharyngeal carcinoma. MATERIALS AND METHODS: Findings in 179 patients (age range, 13-78 years) with American joint Committee on Cancer stage T4M0 nasopharyngeal carcinoma treated from January 1983 to February 1992 with a minimum follow-up of at least 5 years were reviewed. Of the 179 patients, 166 (92.7%) had World Health Organization type II or III disease. Forty-one patients (22.9%) had no lymph nodal involvement; 138 patients (77.1%) had metastatic nodal involvement in the neck. All patients underwent radiation therapy; 39 patients also received different forms of chemotherapy. The radiation therapy doses were usually 70-74 Cy administered to the primary tumor over 7 or 8 weeks, 70-74 Cy to the neck region in patients with nodal involvement, or 50-60 Gy adminstered to the neck region: over 5 or 6 weeks in patients without neck nodal involvement. RESULTS: In 100 patients, radiation therapy failed in the primary tumor alone (n = 28), neck nodes alone (n = 5;), and distant metastases alone (n = 43) or ata combination of sites (n = 24). The cumulative failure rates for the primary tumor, neck metastases, and distant metastases were 25.1% (n = 45), 14.0% (n = 25), and 33.0% (n=59), respectively. The 5-year primary disease-free, distant disease-free, and overall survival rates were 68.7%, 56.5%, and 28.6%,respectively. Results of salvage treatment for relapse were unsatisfactory. CONCLUSION: in about three-tenths of patients, T4M0 nasopharyngeal carcinoma can be cured with conventional high-dose radiation therapy.
Relation:	JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING 9(2):257-265
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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