The role of thallium-201 whole body scan with pelvic SPECT in patients with uterine cervical cancer treated by radiation therapy: a preliminary report

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Title:	The role of thallium-201 whole body scan with pelvic SPECT in patients with uterine cervical cancer treated by radiation therapy: a preliminary report
Authors:	Liang, JA;Kao, CH;Chen, SW;Yang, SN;Sun, SS
Contributors:	附設醫院放射腫瘤科;China Med Univ Hosp, Dept Radiat Therapy & Oncol, Taichung 404, Taiwan;China Med Univ Hosp, Dept Nucl Med, Taichung 404, Taiwan
Date:	2003
Issue Date:	2010-09-24 14:29:42 (UTC+8)
Publisher:	JAPANESE SOCIETY NUCLEAR MEDICINE
Abstract:	Foot problems are the most common cause of hospital admission in patients with type 11 diabetes mellitus (DM). Poor muscle perfusion of lower extremities is thought to be the major component in the pathogenesis of foot problems. Therefore, it is important and interesting to investigate if high prevalence of poor muscle perfusion of lower extremities in type 11 DM patients with abnormal myocardial perfusion and more cardiovascular risk factors. We used a well-established and noninvasive radionuclide method (Xe-133 muscle washout) to objectively evaluate the anterior tibial muscle perfusion of 60 type 11 DM male patients without symptoms/signs of peripheral vascular disease (PVD) in the lower extremities. The patients were separated into groups according to the myocardial perfusion imaging results and cardiovascular risk factor survey. Meanwhile, 30 normal male controls with a matched age distribution were also included for comparison. The muscle perfusions were of significant difference (P-values <.05) between (1) 60 type 11 DM patients (1.84 +/- 0.43 ml/100 g/min) and 30 normal controls (2.95 +/- 0.52 ml/100 g/min), (2) 24 patients with abnormal myocardial perfusion (1.31 +/- 0.45 ml/100 g/min) and 36 patients with normal myocardial perfusion (2.24 +/- 0.48 ml/100 g/min), as well as (3) 28 patients with more cardiovascular risk factors (1.33 +/- 0.46 ml/100 g/min) and 22 patient with less cardiovascular risk factors (2.22 +/- 0.49 ml/100 g/min). Based on Xe-133 muscle washout method, we concluded that the muscle perfusion in the lower extremities of type 11 DM patients without symptoms/signs of PVD is significantly decreased and related to abnormal myocardial perfusion and more cardiovascular risk factors. (C) 2003 Elsevier Inc. All rights reserved.
Relation:	ANNALS OF NUCLEAR MEDICINE 17(7):613-617
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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