CYP17 and tumor necrosis factor-alpha gene polymorphisms are associated with risk of oral cancer in Chinese patients in Taiwan

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 台中附設醫院 > 期刊論文 > Item 310903500/29253

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.cmu.edu.tw/ir/handle/310903500/29253

题名:	CYP17 and tumor necrosis factor-alpha gene polymorphisms are associated with risk of oral cancer in Chinese patients in Taiwan
作者:	Chen, WC;Tsai, MH;Lei, W;Chen, WC;Tsai, CH;Tsai, FJ
贡献者:	附設醫院兒科部;China Med Univ, Dept Pediat, Taichung, Taiwan;Taichung Healthcare & Management Univ, Dept Urol, Taichung, Taiwan;Coll Chinese Med, Taichung, Taiwan;Coll Chinese Med, Taichung, Taiwan;Dept Med Genet, Taichung, Taiwan;Dept Otolaryngol, Taichung, Taiwan
日期:	2005
上传时间:	2010-09-24 14:29:02 (UTC+8)
出版者:	TAYLOR & FRANCIS AS
摘要:	Objective: The aim of the study was to evaluate the association between intraocular pressure (IOP) and several systemic health parameters in Taiwan. Methods: We retrospectively reviewed the medical records from all participants who had been examined in China Medical University Hospital. A total of 1,271 subjects (mean age, 50.0 +/- 12.0 years; age range, 21 to 85) who had not undergone any medical treatment for ocular hypertension or glaucoma were included in this study. Systemic factors (age, sex, blood pressure, total cholesterol, triglycerides, fasting glucose, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, body mass index, waist circumference) were measured. One-way analysis of variance, Pearson correlation coefficients, and multivariate linear regression were used. Results: There were 674 (53.0%) males and 597 (47.0%) females in this study. After controlling for the other covariates, the multivariate linear regression analysis showed that in males and females, systolic blood pressure was positively associated with IOP. That is, a change in systolic blood pressure by 1 mm Hg would alter the measured IOP by 0.024 mm Hg in males (95% Cl, 0.002, 0.046; P = 0.031) and 0.030 mm Hg in females (95% Cl, 0.006, 0.053; P = 0.014). In males, age was inversely associated with IOP. That is, a change in age by 1 year would alter the measured IOP by -0.039 mm Hg (95% CL -0.059, -0.020; P = 0.0001). Conclusions: IOP was found to have a strong positive association with systolic blood pressure in males and females. IOP was inversely associated with age in males. This study may provide basic information for further studies on IOP in Taiwan.
關聯:	ACTA OTO-LARYNGOLOGICA 125(1):96-99
显示于类别:	[台中附設醫院] 期刊論文

文件中的档案:

没有与此文件相关的档案.

在CMUR中所有的数据项都受到原著作权保护.

TAIR相关文章

数据加载中.....