Acute pyelonephritis and sequelae of renal scar in pediatric first febrile urinary tract infection

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Title:	Acute pyelonephritis and sequelae of renal scar in pediatric first febrile urinary tract infection
Authors:	Lin, KY;Chiu, NT;Chen, MJ;Lai, CH;Huang, JJ;Wang, YT;Chiou, YY
Contributors:	附設醫院兒科部;Natl Cheng Kung Univ, Med Ctr, Dept Pediat, Tainan 704, Taiwan;Natl Cheng Kung Univ, Med Ctr, Inst Clin Med, Tainan 704, Taiwan;Natl Cheng Kung Univ, Coll Med, Tainan 70101, Taiwan;Natl Cheng Kung Univ, Med Ctr, Dept Nucl Med, Tainan 704, Taiwan;Chung Hwa Inst Technol, Dept Nursing, Tainan, Taiwan;China Med Coll Hosp, Dept Pediat, Taichung, Taiwan;Natl Cheng Kung Univ, Med Ctr, Dept Internal Med, Tainan 704, Taiwan;Natl Cheng Kung Univ, Med Ctr, Inst Clin Med, Tainan 704, Taiwan;Chi Mei Fdn Hosp, Dept Pediat, Tainan, Taiwan
Date:	2003
Issue Date:	2010-09-24 14:27:04 (UTC+8)
Publisher:	SPRINGER-VERLAG
Abstract:	Volatile anesthetics such as halothane and isoflurane have long been thought to affect pulmonary function. The purpose of this study was to examine whether volatile anesthetics (halothane and isoflurane) can induce pulmonary vascular endothelium damage. Before surgery, 1 h after surgery, and 1 week after surgery, the degree of pulmonary vascular endothelium damage was represented as increased lung/liver uptake ratios (L/L ratio) and measured on technetium-99m hexamethylpropylene amine oxime (Tc-99m HMPAO) lung scan in 3 groups of the patients. Group 1 included 20 patients undergoing surgery and receiving volatile anesthesia with 1% halothane. Group 2 included 20 patients undergoing surgery and receiving volatile anesthesia with 1.5% isoflurane. Group 3 included 20 patients undergoing surgery with intravenous anesthesia drugs. No significant change of L/L ratio was found from before surgery, 1 h after surgery, to 1 week after surgery in group 3 patients. In groups 1 and 2 patients, significantly transient increased L/L ratio was found 1 h after surgery. We conclude that volatile anesthesia (halothane and isoflurane) can induce transient pulmonary vascular endothelium damage, represented as transiently increased L/L ratios on Tc-99m HMPAO lung scan.
Relation:	PEDIATRIC NEPHROLOGY 18(4):362-365
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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