Behavioral/environmental intervention improves learning after cerebral hypoxia-ischemia in rats

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Please use this identifier to cite or link to this item: http://ir.cmu.edu.tw/ir/handle/310903500/29185

Title:	Behavioral/environmental intervention improves learning after cerebral hypoxia-ischemia in rats
Authors:	Chou, IC;Trakht, T;Signori, C;Smith, J;Felt, BT;Vazquez, DM;Barks, JDE
Contributors:	附設醫院兒科部;Univ Michigan, Dept Pediat, Ann Arbor, MI 48109 USA;Univ Michigan, Ctr Human Growth & Dev, Ann Arbor, MI 48109 USA;China Med Coll Hosp, Dept Pediat, Taichung, Taiwan
Date:	2001
Issue Date:	2010-09-24 14:25:53 (UTC+8)
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Abstract:	The purpose of this study was to evaluate if IL-1 beta (IL-1 beta promoter and IL-1 beta exon 5) and IL-Ireceptor antagonist (IL-1Ra) gene polymorphisms act as markers of susceptibility to or severity of RA. The study included 104 RA patients and 103 normal controls. No significant difference was observed in the cytokine allelic frequencies of IL-1 beta promoter and IL-1 beta exon 5 between patients with RA and healthy controls. In addition, there was no significant association in the cytokine carriage rates of I and II allele of IL-1Ra between RA patients and healthy controls. In contrast. the IV allele of IL-1Ra was significantly increased in RA patients with low inflammatory activity (P = 0.03). This study indicated that allelic frequency and carriage rate of IL-1 beta (IL-1 beta) promoter and IL-1 beta exon 5) and IL-1Ra (I and II allele) do not differ significantly between normal controls and RA patients in Taiwan. However. the carriage rate of IV allele of IL-1Ra was high in the RA patients with low inflammatory activity.
Relation:	STROKE 32(9):2192-2197
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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