Successful prenatal digoxin therapy for Ebstein's anomaly with hydrops fetalis - A case report

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Title:	Successful prenatal digoxin therapy for Ebstein's anomaly with hydrops fetalis - A case report
Authors:	Hsieh, YY;Lee, CC;Chang, CC;Tsai, HD;Yeh, LS;Tsai, CH
Contributors:	附設醫院兒科部;China Med Coll Hosp, Dept Pediat, Taichung, Taiwan;China Med Coll Hosp, Dept Obstet & Gynecol, Taichung, Taiwan
Date:	1998
Issue Date:	2010-09-24 14:25:09 (UTC+8)
Publisher:	SCI PRINTERS & PUBL INC
Abstract:	Objectives: To investigate chromium-induced renal dysfunction in electroplating workers. Methods: A cross-sectional study was used to evaluate four biochemical markers of renal function. A total of 178 workers were divided into 3 comparable groups consisting of 34 hard-chrome plating workers, 98 nickel-chrome electroplating workers, and 46 aluminum anode-oxidation workers, who represented the reference group. Ambient and biological monitoring of urinary chromium were performed to measure exposure concentrations. Results: Overall, urinary chromium concentrations were highest among hard-chrome plating workers (geometric mean 2.44 mu g/g creatinine), followed by nickel-chrome electroplating workers (0.31 mu g/g creatinine) and aluminum workers (0.09 mu g/g creatinine). Airborne chromium concentrations were also highest in the hard-chrome plating area (geometric mean 4.20 mu g/m(3)), followed by the nickel-chrome electroplating area (0.58 mu g/m(3)) and the aluminum area (0.43 mu g/m(3)). A positive correlation was found between urinary chromium and airborne concentrations (r = 0.54, P < 0.01). Urinary concentrations of N-acetyl-beta-D-glucosaminidase (NAG) were also highest among hard-chrome plating workers (geometric mean 4.9 IU/g creatinine)? followed by nickel-chrome workers (3.4 IU/g creatinine) and aluminum workers (2.9 IU/g creatinine). The prevalence of "elevated" NAG (>7 IU/g creatinine) was significantly highest among hard-chrome plating workers (23.5%), then among nickel-chrome workers (7.1%) and aluminum workers (8.7%). Differences in beta(2)-microglobulin, total protein, and microalbumin were not significant. Conclusion: The author's evidence indicates that NAG is an early indicator of renal dysfunction in hard-chrome plating workers.
Relation:	JOURNAL OF REPRODUCTIVE MEDICINE 43(8):710-712
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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