Detection of Epstein-Barr virus-derived latent membrane protein-1 gene in various head and neck cancers: Is it specific for nasopharyngeal carcinoma?

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Title:	Detection of Epstein-Barr virus-derived latent membrane protein-1 gene in various head and neck cancers: Is it specific for nasopharyngeal carcinoma?
Authors:	Tsang, NM;Chang, KP;Lin, SY;Hao, SP;Tseng, CK;Kuo, TT;Tsai, MH;Chung, TC
Contributors:	附設醫院耳鼻喉部;Chang Gung Univ, Chang Gung Mem Hosp, Dept Otolaryngol Head & Neck Surg, Chang Gung Canc Ctr, Taipei, Taiwan;Chang Gung Mem Hosp, Dept Radiat Oncol, Chang Gung Canc Ctr, Taipei, Taiwan;Chang Gung Mem Hosp, Dept Pathol, Chang Gung Canc Ctr, Taipei, Taiwan;China Med Coll Hosp, Dept Otolaryngol, Taichung, Taiwan;Taipei Med Univ, Sch Med Technol, Taipei, Taiwan;Natl Taiwan Univ, Coll Med, Grad Inst Med Technol, Taipei 10018, Taiwan
Date:	2003
Issue Date:	2010-09-24 14:24:16 (UTC+8)
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Abstract:	Congenital intracranial tumors are rare and only account for 0.5 to 1.5 % of all pediatric brain tumors. Teratoma is the most frequently encountered intracranial tumor at birth. Cephalomegaly and hydrocephalus are the usual clinical presentations. Advances in imaging techniques have improved diagnostic accuracy in congenital brain tumors. But the prognosis of a massive intracranial teratoma is always dismal. We report a congenital mixed malignant germ cell tumor in a male fetus at 27 weeks of gestation, with massive involvement of cerebrum and orbit. According to histological and immunohistochemical studies, the tumor was made up of predominantly immature teratoma combined with a yolk sac tumor. To our knowledge, such a combination has not been well documented in the literature.
Relation:	LARYNGOSCOPE 113(6):1050-1054
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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