We describe a 70-year-old man with fulminant adult T-cell leukemia/lymphoma. He died of progressive disease 1 week after the onset of symptoms. The integrated viral DNA of human T-lymphotropic virus type 1 was detected in the bone marrow aspirate by polymerase chain reaction. Cytogenetic analysis of bone marrow cells showed novel clonal aberrations consisting of 46,XY.der(8)t(8;14)(p11;q11),del(9) (q13q22),t(14;22)(q13;q13). (C) Elsevier Science Inc. All rights reserved.
關聯:
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION 101(11):795-797