PHOTOAGEING-ASSOCIATED MITOCHONDRIAL-DNA LENGTH MUTATIONS IN HUMAN SKIN

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Title:	PHOTOAGEING-ASSOCIATED MITOCHONDRIAL-DNA LENGTH MUTATIONS IN HUMAN SKIN
Authors:	YANG, JH;LEE, HC;WEI, YH
Contributors:	附設醫院皮膚科;NATL YANG MING UNIV,SCH LIFE SCI,DEPT BIOCHEM,TAIPEI 112,TAIWAN;CHINA MED COLL & HOSP,DEPT DERMATOL,TAICHUNG,TAIWAN;NATL YANG MING UNIV,INST CLIN MED,TAIPEI,TAIWAN
Date:	1995
Issue Date:	2010-09-24 14:23:50 (UTC+8)
Publisher:	SPRINGER VERLAG
Abstract:	Panax ginseng, one of the most widely used plant medicines, was combined with radiotherapy, and studied against intrahepatic sarcoma-180 tumour cells in mice, Oral administration of ginseng extract, radiation treatment and the combination of both increased the life span of tumour-bearing mice to 20.4%, 16.9% and 82.1%, respectively,.The same treatments were found to be cytotoxic to sarcoma-180-induced liver tumour cells, The synthetic rates of DNA, RNA and protein of the tumour cells were all inhibited measurably by the combined treatment, Histopathological studies showed that radiation treatment destroyed both cancer and liver cells and the cells shrank and became necrotic. The ginseng treatment seemed to help the recovery of liver cells and no infiltration of cancer cells was noted.
Relation:	ARCHIVES OF DERMATOLOGICAL RESEARCH 287(7):641-648
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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