Role of leukocyte count, neutrophil percentage, and C-reactivc protein in the diagnosis of acute appendicitis in the elderly

CMUR > China Medical University Hospital > Jurnal articles > Item 310903500/29137

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Title:	Role of leukocyte count, neutrophil percentage, and C-reactivc protein in the diagnosis of acute appendicitis in the elderly
Authors:	Yang, HR;Wang, YC;Chung, PK;Chen, WK;Jeng, LB;Chen, RJ
Contributors:	附設醫院外科部;China Med Univ Hosp, Dept Surg, Taichung 404, Taiwan;China Med Univ Hosp, Dept Emergency Med, Taichung 404, Taiwan
Date:	2005
Issue Date:	2010-09-24 14:23:27 (UTC+8)
Publisher:	SOUTHEASTERN SURGICAL CONGRESS
Abstract:	Objective. To estimate in a Chinese population the prevalence of undifferentiated spondyloarthropathy (USpA) among first-degree relatives (FDRs) of ankylosing spondylitis (AS) probands, and to compare the clinical features of familial USpA with those of sporadic USpA. Methods. The FDRs of two separate cohorts of consecutive AS probands were evaluated for the prevalence of USpA, using the Modified New York criteria and the European Spondylitis Study Group criteria for AS and SpA, respectively. Sporadic USpA and FDRs of non-SpA rheumatic patient probands served as separate controls. Results. Among the 301 FDRs of 102 AS probands, 7.0% were USpA. This was 1000 times higher than the 147 FDRs of 40 non-SpA probands (P = 0.00230). Within the AS families, USpA was less male-dominated than AS (33.3 vs 72.5%) (P = 0.006). The only feature distinguishing familial from sporadic USpA was that the percentages of HLA B27 were 100 and 50%, respectively (P < 0.001). Conclusion. USpA and AS coexist in the same Chinese families, both being predisposed by HLA B27. In these families, a female gender favours the development of USpA rather than AS. A significant subset of sporadic USpA (HLA B27-negative group) has a different genetic predisposition compared with familial USpA.
Relation:	AMERICAN SURGEON 71(4):344-347
Appears in Collections:	[台中附設醫院] 期刊論文

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