3-D US frame positioning using speckle decorrelation and image registration

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 台中附設醫院 > 期刊論文 > Item 310903500/29125

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題名:	3-D US frame positioning using speckle decorrelation and image registration
作者:	Chang, RF;Wu, WJ;Chen, DR;Chen, WM;Shu, W;Lee, JH;Jeng, LB
貢獻者:	附設醫院外科部;China Med Coll & Hosp, Dept Gen Surg, Taichung, Taiwan;Natl Chung Cheng Univ, Dept Comp Sci & Informat Engn, Chiayi, Taiwan
日期:	2003
上傳時間:	2010-09-24 14:22:51 (UTC+8)
出版者:	ELSEVIER SCIENCE INC
摘要:	The chemopreventive role of 5-methoxypsoralen (5-MOP) in the human hepatocellular carcinoma (HCC) cell line was investigated by studying the regulation of proliferation and apoptosis in HCC (J5) cells. Morphological analysis, cell viability assay, DNA analysis and cell-cycle analysis suggest that there are at least three modes of the suppressive effects shown by 5-MOP: (a) kills J5 cells directly; (b) induces apoptosis by arresting J5 cells at the G2/M phase in the cell cycle; (c) induces apoptosis through an independent pathway with cell-cycle arrest at 24-72 h of exposure. Further immunoblot analysis demonstrated that inhibition of cyclin B1 by 5-MOP may play an important role in G2/M arrest of J5 cells and provides an additional way to prevent cells from entering the M phase and undergoing apoptosis. 5-MOP therefore appears to exert its anticarcinogenic properties by cytotoxic effect, inducing apoptosis and inhibiting proliferation in the human hepatocellular carcinoma cell line. (C) 2003 Elsevier Science Ltd. All rights reserved.
關聯:	ULTRASOUND IN MEDICINE AND BIOLOGY 29(6):801-812
顯示於類別:	[台中附設醫院] 期刊論文

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