中國醫藥大學機構典藏 China Medical University Repository, Taiwan:Item 310903500/29124
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    题名: Comparing thallium-201 spect mammoscintigraphy and ultrasonography to detect breast cancer in mammographical dense breasts
    作者: Chen, DR;Jeng, LB;Kao, A;Lin, CC;Lee, CC
    贡献者: 附設醫院外科部;China Med Coll Hosp, Dept Surg, Taichung 404, Taiwan;China Med Coll Hosp, Dept Nucl Med, Taichung 404, Taiwan;China Med Coll Hosp, Dept Family Med, Taichung 404, Taiwan;China Med Coll Hosp, Dept Med Res, Taichung 404, Taiwan
    日期: 2003
    上传时间: 2010-09-24 14:22:49 (UTC+8)
    出版者: VEDA, SLOVAK ACADEMY SCIENCES
    摘要: Background and Purpose: Many preventative strategies have been proposed to control hepatitis C virus (HCV) infection in the hemodialysis unit. The effectiveness of isolation as a preventive policy remains unclear. The aim of this study was to evaluate the effect of an isolation policy on the incidence of hepatitis C in our hemodialysis unit. Methods. A total of 325 hemodialysis patients with a mean age of,62 14 years and a mean duration of dialysis of 4.8 +/- 4.4 years, who were treated from January 1993 to December 2000 were included in this retrospective study. Data were collected from medical records. HCV antibody was monitored at 6-month intervals. During the period before September 1997 all patients were dialyzed in a single room. Isolation started after September 1997, when an additional room became available. Patients positive for either hepatitis B or C were clustered in 1 area (Area 1). Anti-HCV-negafive and hepatitis B surface antigen (HBsAg)-negative patients were assigned either to a segregated zone (Area 2) adjacent to Area 1 in the same room or to a separate independent room (Area 3). Dialyzers were not reused and hygienic precautions remained the same throughout the study period. Results: Forty months after the implementation of the isolation policy, there was significant reduction in the total prevalence (49.7 vs 31.7%, p < 0.01) and incidence (9.1 vs 2.9 % patient-years, p < 0.01) of HCV infection. Seroconversion of anti-HCV was detected in 9 patients, 7 in Area 1, 2 in Area 2, with no new cases in Area 3. The incidence of seroconversion of anti-HCV was significantly different in the 3 areas. Regression analysis indicated that isolation was the most prominent independent factor in reducing seroconversion of anti-HCV. Conclusions: These results support the use of an isolation policy to combat HCV infection among hemodialysis patients, particularly in high prevalence units.
    關聯: NEOPLASMA 50(3):222-226
    显示于类别:[台中附設醫院] 期刊論文

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