Hydrops foetalis caused by anti-mur in first pregnancy-a case report

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Title:	Hydrops foetalis caused by anti-mur in first pregnancy-a case report
Authors:	巫康熙(Kang-His Wu);張建國;林媽利(ML Lin);施木青(Mu-Chin Shih);林鴻志(Hung-Chih Lin);李建忠(CC Lee)*;彭慶添(Ching-Tien Peng);蔡長海(Chang-Hai Tsai)
Contributors:	中醫學院中醫學系學士班中醫內科學科;中國附醫兒童醫學中心小兒血液腫瘤科
Keywords:	anti-Mur;hydrops foetalis
Date:	2002
Issue Date:	2009-08-20 17:57:36 (UTC+8)
Abstract:	SummaryAnti-'Mia' is the most common alloantibody of potential clinical significance in the Taiwanese population. The Mi.III phenotype is rare among Caucasians but has a high incidence in various Oriental populations. We describe a nulliparous woman with no history of transfusions, who had hydrops foetalis at 28 weeks gestation. Foetal haemoglobin was 4·4 g dL−1, and a positive direct antiglobulin test was positive in the foetal blood. Intrauterine intravascular transfusion was given, and the baby was discharged healthy. Anti-'Mia' was identified in the maternal serum, the cord blood serum and the eluate from red cells of the cord blood. Anti-'Mia' in the maternal serum was confirmed to be anti-Mur. The polymerase chain reaction-restriction fragment length polymorphism method confirmed that both the baby and her father had the Mi.III gene. Therefore, our report documents that anti-Mur has the potential to cause hydrops foetalis.
Relation:	TRANSFUSION MEDICINE AND HEMOTHERAPY12(1):325~327?
Appears in Collections:	[School of Chinese Medicine] Journal articles

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