ANTITRICHOMONAL ACTION OF EMODIN IN MICE

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Title:	ANTITRICHOMONAL ACTION OF EMODIN IN MICE
Authors:	WANG, HH
Contributors:	附設醫院內科部消化科;WANG, HH, CHINA MED COLL HOSP,DEPT INTERNAL MED,DIV GASTROENTEROL,TAICHUNG 40408,TAIWAN
Date:	1993
Issue Date:	2010-09-24 14:20:46 (UTC+8)
Publisher:	ELSEVIER SCI IRELAND LTD
Abstract:	The effects of moxibustion on experimental hyperbilirubinemia and cholangitis were studied in male rats (n = 33). The experimental group were treated with moxibustion, 18, 12 and 6 hours prior to and 6, 12 and 18 hours after challenge with oral alpha-napthylisothiocyanate (ANIT, 100 mg per kg). Rats were sacrificed 48 hours after challenge. Serum and liver samples were taken for biochemical and histological analysis, respectively. The results revealed that rats treated with ANIT exhibited elevations in bilirubin, SGOT and SGPT as well as cholangitis. In rats receiving moxibustion and ANIT, biochemical and morphological parameters of liver injury were significantly reduced. Thus, this study shows that moxibustion therapy may be able to prevent ANIT-induced hyperbilirubinemia and cholangitis.
Relation:	JOURNAL OF ETHNOPHARMACOLOGY 40(2):111-116
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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