The epidemiology of hyperuricaemia and gout in Taiwan aborigines

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Title:	The epidemiology of hyperuricaemia and gout in Taiwan aborigines
Authors:	Chou, CT;Lai, JS
Contributors:	附設醫院內科部風濕免疫科;China Med Coll Hosp, Div Rheumatol Immunol, Dept Med, Taichung, Taiwan;China Med Coll, Dept Publ Hlth, Taichung, Taiwan
Date:	1998
Issue Date:	2010-09-24 14:20:35 (UTC+8)
Publisher:	OXFORD UNIV PRESS
Abstract:	Three new flavonoids, (3R)-4'-methoxy-2',3,7-trihydroxyisoflavanone (11), 7-methoxy-3.3',4',6-tetrahydroxyflavone (18), and 2',7-dihydroxy-4',5'-dimethoxyisoflavane (22), were isolated from the heartwood of Dolbergia odorifera T. Chen. (Leguminosae), together with twenty-two known compounds, (S)-4-methoxydalbergione (1), cearoin (2), medicarpin (3), formononetin (4), sativanone (5), 3-hydroxy-9-methoxycoumestan (6), meliotocarpan A (7), isoliquiritigenin (8), stevein (9), liquiritigenin (10), 3',4',7-trihydroxyflavanone (12), butein (13), 3'-hydroxymelanettin (14), koparin (15), bowdichione (16), fisetin (17), melanettin (19), sulfuretin (20), 3'-hydroxydaidzein (21), 3'-O-methylviolanone (23), xenognosin B (24), and dalbergin (25). These flavonoids were evaluated in antiallergic and anti-inflammatory tests. The results showed that (5)4-methoxydalbergione (1) and cearoin (2) exhibited antiallergic activity while (S)-4-methoxydalbergione (1), cearoin (2), butein (13), koparin (15), bowdichione (16), 3'-O-methylviolanone (23), and xenognosin B (24) showed significant anti-inflammatory activity.
Relation:	BRITISH JOURNAL OF RHEUMATOLOGY 37(3):258-262
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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